Noise Reduction the Open Source way

What are your options when you don’t run Windows or Mac and/or don’t want to use proprietary software?
Niklas Saers covers some of the options in this blog post. Thanks to him, I learned about ISO Noise Reduction, a GIMP plugin, which I’ll give a try tomorrow.
I usually use DCAM Noise, or selective blur to remove offending pixels but that can leave awful looking smooth areas next to unsightly pixels.